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The ACP double–syringe system is designed for the efficient and safe preparation of autologous platelet–rich plasma (PRP) directly at the patient’s point of care. This system enables the quick processing of a small blood sample to produce PRP, which can be combined with autograft and allograft bone before being applied to an orthopaedic surgical site, based on clinical needs. There is growing interest in the use of autologous blood

In countries that recognize the CE mark, the ACP system is indicated for the treatment of knee osteoarthritis, rotator cuff repair, and elbow tendinosis.

Reference:

De Girolamo L, Laver L. The Use of Injectable Orthobiologics for Knee Osteoarthritis: A Formal ESSKA

Consensus, Part 1:

Blood-Derived Products (PRP). 2022. www.esska.org/page/projects

Choosing the Right Patient: Deciding who will benefit the most from PRP treatment for knee osteoarthritis is complex and depends on many factors.

Evidence for PRP :

There is enough research to support using PRP to treat knee osteoarthritis. PRP vs. HA: Experts recommend PRP over hyaluronic acid (HA) for knee osteoarthritis because it tends to improve symptoms more and lasts longer. However, different PRP products can affect study results.

Types of PRP:

Both leukocyte-poor PRP (LP-PRP) and leukocyte-rich PRP (LR-PRP) are good options for treating knee osteoarthritis. Injection Plan: It’s recommended to get 2-4 PRP injections, spaced 1-3 weeks apart.

Comparing PRP and Corticosteroid Injections for Knee Osteoarthritis

Reference:

Double-Blind Randomized Controlled Trial Comparing Platelet-Rich Plasma With Intra-Articular Corticosteroid Injections in Patients With Bilateral Knee Osteoarthritis. Cureus. 2022;14(9). doi:10.7759/cureus.29744

Study Design:

This study involved 29 patients with mild-to-moderate knee osteoarthritis. Each patient received a PRP injection in one knee and a corticosteroid injection in the other knee.

Follow-Up:

The patients were checked at 6 weeks, 3 months, and 6 months after the injections.

Results:

Both types of injections helped reduce pain, stiffness, and improve knee function. The biggest improvements were noticed at 6 weeks and 3 months.

Comparison:

There was no significant difference in how well PRP and corticosteroid injections worked.

Comparison of PRP and Hyaluronic Acid for Knee Osteoarthritis: Meta-Analysis of 26 RCTs

Reference:

Platelet-Rich Plasma Versus Hyaluronic Acid in the Treatment of Knee Osteoarthritis: A Meta- Analysis of 26 Randomized Controlled Trials. Arthroscopy. 2021 Jan;37(1):309-325. doi: 10.1016/j.arthro.2020.07.011.

Study Overview:

This meta-analysis included 26 randomized controlled trials with a total of 2430 patients comparing PRP to hyaluronic acid (HA) for treating knee osteoarthritis.

Better Outcomes with PRP :

Patients who received PRP had better scores in pain (VAS), overall knee function (WOMAC total), and physical function (WOMAC physical function) at 3, 6, and 12 months compared to those who received HA.

Improvement in Specific Areas:

PRP also showed better results in pain (WOMAC pain), stiffness (WOMAC stiffness), quality of life (EuroQol VAS), and knee function (IKDC) at 6 and 12 months.

Safety:

There was no significant difference in adverse events between the PRP and HA groups, indicating both treatments are similarly safe.

ACP double Syringe

Reference:

Consensus, Part 1:

Evidence for PRP :

Types of PRP:

Reference:

Study Design:

Follow-Up:

Results:

Comparison:

Reference:

Study Overview:

Better Outcomes with PRP :

Improvement in Specific Areas:

Safety:

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